New publication on Integral Membrane Protein Oligomers Isolation

CALIXAR Team is happy to announce its recent publication in collaboration with Philippe DETERRE (Pierre and Marie Curie University of Paris – Center of Immunology and Infectious Diseases – Chemokines in pathologies and Inflammation Team).

This research work illustrates the advantage of using CALIXAR’s approach to isolate and characterize integral membrane protein oligomers such as this reported case study of the Transmembrane Chemokine CX3CL1.

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Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.

  • Conformational antibody development
  • Vaccine development
  • High-throughput ligand screening
  • Structure-based drug discovery
  • Immunoassays
  • Deorphanization projects
  • Identification of relevant targets
  • Expression of full-length membrane proteins
  • Functional isolation and stabilization of targets

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