Purified Membrane Proteins

Monocarboxylate transporter 4

Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate. Plays a predominant role in the transport of L-lactate efflux from highly glycolytic cells (By similarity).

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

MOT4_HUMAN

Gene Name:

SLC16A3

Uniprot Accession:

O15427

Origin:

Homo sapiens (Human)

Protein family:

Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13)

Full-length:

465

Mass:

49469

Sequence

MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

Monocarboxylate transporter 4

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