Purified Membrane Proteins

ATP synthase protein 8

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) – containing the extramembraneous catalytic core and F(0) – containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

ATP8_HUMAN

Gene Name:

MT-ATP8

Uniprot Accession:

P03928

Origin:

Homo sapiens (Human)

Protein family:

ATPase protein 8

Full-length:

68

AA

Mass:

7992

Da

MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLPPSPKPMKMKNYNKPWEPKWTKICSLHSLPPQS

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes