Purified Membrane Proteins

Interferon alpha-inducible protein 6

Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

IFI6_HUMAN

Gene Name:

IFI6

Uniprot Accession:

P09912

Origin:

Homo sapiens (Human)

Protein family:

IFI6/IFI27

Full-length:

130

Mass:

12927

Sequence

MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKYLDSEEDEE

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

Interferon alpha-inducible protein 6

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