Purified Membrane Proteins

Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulate SERCA pump activity. Enhances sarcoplasmic reticulum Ca(2+) uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN).

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

DWORF_HUMAN

Gene Name:

STRIT1

Uniprot Accession:

P0DN84

Origin:

Homo sapiens (Human)

Protein family:

nd

Full-length:

35

AA

Mass:

3836

Da

MAEKAGSTFSHLLVPILLLIGWIVGCIIMIYVVFS

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