Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)

Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport (By similarity). {ECO:0000250|UniProtKB:P18581, ECO:0000269|PubMed:9174363}.; [Isoform 1]: Functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. {ECO:0000269|PubMed:9174363}.; [Isoform 2]: Functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). {ECO:0000269|PubMed:9174363}.