Purified Membrane Proteins

Low-density lipoprotein receptor class A domain-containing protein 3

May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation.; (Microbial infection) Acts as a receptor for Venezuelan equine encephalitis virus.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

LRAD3_HUMAN

Gene Name:

LDLRAD3

Uniprot Accession:

Q86YD5

Origin:

Homo sapiens (Human)

Protein family:

LDLR

Full-length:

345

Mass:

37419

Sequence

MWLLGPLCLLLSSAAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSANSASSQAASSLLSVEDTSHSPGQPGPQEGTAEPRDSEPSQGTEEV

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

Low-density lipoprotein receptor class A domain-containing protein 3

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