Purified Membrane Proteins

DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator)

Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. {ECO:0000269|PubMed:16839881, ECO:0000269|PubMed:17304243}.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

DRAM1_HUMAN

Gene Name:

DRAM1 DRAM

Uniprot Accession:

Q8N682

Origin:

Homo sapiens (Human)

Protein family:

DRAM/TMEM150 family

Full-length:

238

AA

Mass:

26253

Da

MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes