Purified Membrane Proteins

G protein-activated inward rectifier potassium channel 3

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

KCNJ9_HUMAN

Gene Name:

KCNJ9

Uniprot Accession:

Q92806

Origin:

Homo sapiens (Human)

Protein family:

Inward rectifier-type potassium channel (TC 1.A.2.1), KCNJ9 subfamily

Full-length:

393

Mass:

44020

Sequence

MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGADKEQNGCLPPPESESKV

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
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G protein-activated inward rectifier potassium channel 3

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