Purified Membrane Proteins

Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial

Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

COX16_HUMAN

Gene Name:

COX16

Uniprot Accession:

Q9P0S2

Origin:

Homo sapiens (Human)

Protein family:

COX16

Full-length:

106

AA

Mass:

12293

Da

MFAPAVMRAFRKNKTLGYGVPMLLLIVGGSFGLREFSQIRYDAVKSKMDPELEKKLKENKISLESEYEKIKDSKFDDWKNIRGPRPWEDPDLLQGRNPESLKTKTT

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes