Membrane Protein Pipeline

No matter the goals of your project or needs of your team, CALIXAR has the most powerful membrane protein services and technology to get you where you want to be.

OUR PIPELINE

A2A

CALIXAR’s A2A GPCR aids in the discovery, improvement, and validation of therapeutic antibodies, as well as insomnia, Alzheimer and Parkinson diseases.

MT1

CALIXAR's MT1 GPCR assists in the discovery, improvement, validation of new molecules and therapeutic antibodies for CNS neuroprotection.

AcrB

CALIXAR’s AcrB transporter aids in the identification, development, refinement, and validation of new molecules and therapeutic antibodies.

BmrA

CALIXAR’s BmrA transporter acts as a mechanical pump for ATP dependent drug efflux. This unique characteristic makes BmrA transporters a powerful therapeutic target for multi-drug resistance studies.

KCC2

CALIXAR’s KCC2 ion channel assists in the discovery and validation of new molecules or antibodies. They are ideal candidates for neurological diseases like pain and epilepsy.

Contact us

Secure and boost your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.

  • Conformational antibody development
  • Vaccine development
  • High-throughput ligand screening
  • Structure-based drug discovery
  • Immunoassays
  • Deorphanization projects
  • Identification of relevant targets
  • Expression of full-length membrane proteins
  • Functional isolation and stabilization of targets

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