Soft Proprietary Detergents
CALIXAR’s CALX8 reagent is a ionic calixarene based detergent/surfactant with three polar carboxylic groups and a octyl chain.
Compound name: CALX8
Catalogue number: CALX8_50MG,
Molec. Formula: C42H43Na3O10
MW: 776.7 g/mol
Percent Composition: C, 64.94; H, 5.58; N, 8.88; O, 20.60
Physical state: Beige powder
Purity (HPLC, 214nm): nd
Retention time (RP18 HPLC): nd
CMC: 2.2 mM
Exact mass: 776.2549
Stability: Store in <-20°C freezer for up to one year
Solubility Structure: Soluble in methanol, DMSO and water
€ 1,200.00 (50mg)
€ 1,900.00 (100mg)
€ 3,000.00 (250mg)
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Why choose us?
The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time.
CALIXAR’s CALX8 is in powder form and is used in an aqueous solution or buffer. CALX8 can be combined with biological materials (such as biological membranes).
Our clients are able to use CALX8 to assist in the development of lipid detergents, mixed micelles, and protein detergent micelles. CALX8 enables clients to extract, solubilize and stabilize native and functional membrane proteins in a solution.
CALX8 is very mild detergent to secure, to solubilize and to preserve native membrane proteins. It is also not sensitive to ionic strength or pH variations which is ideal for extraction, to solubilization and to stabilization of particular membrane proteins.
CALIXA’s CALX8 is non-ionic and consequently is not susceptible to ionic strength or pH variations and is adapted to extract, to solubilize or to stabilize precise membrane proteins.
CALIXAR’s CALX8 extracts high-quality membrane proteins that are utilized for pharmaceutical research, discovery and, structural studies. Our CALX8 is used by biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.
Desuzinges Mandon E. et al. 2017