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CALX8

CALX8 solubilizing reagent

Biological information

Background
CALX8 or 5,11,17-tris[(carboxy)methyl]-25-monooctyloxy-26,27,28-trihydroxycalix[4]arene solubilizing reagent is a calixarene based detergent/surfactant with three polar carboxylic groups and a octyl chain. This detergent is adapted to extract, to solubilize or to stabilize precise membrane proteins. The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time. CALX8 is in powder form and is used in an aqueous solution or buffer. It can be combined with biological materials (such as biological membranes). CALX8 is very mild detergent to secure, to solubilize and to preserve native membrane proteins which is ideal for extraction, to solubilization and to stabilization of particular membrane proteins. Our clients are able to use CALX8 to assist in the development of lipids-detergents mixed micelles, and protein detergent micelles.
Target class
Solubilizing Reagent
Family
Accession number
Target Name
CALX8
Target Alias
Origin
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
For Research Only
Storage conditions
Store in < -20 °C freezer out of direct light for a long-term storage
Usage disclaimer
For Research Only

Chemical data

Background
CALX8 or 5,11,17-tris[(carboxy)methyl]-25-monooctyloxy-26,27,28-trihydroxycalix[4]arene solubilizing reagent is a calixarene based detergent/surfactant with three polar carboxylic groups and a octyl chain. This detergent is adapted to extract, to solubilize or to stabilize precise membrane proteins. The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time. CALX8 is in powder form and is used in an aqueous solution or buffer. It can be combined with biological materials (such as biological membranes). CALX8 is very mild detergent to secure, to solubilize and to preserve native membrane proteins which is ideal for extraction, to solubilization and to stabilization of particular membrane proteins. Our clients are able to use CALX8 to assist in the development of lipids-detergents mixed micelles, and protein detergent micelles.
Compound name
Solubilizing Reagent
Catalog number
40-D101P-50MG
Molecular formula
C42H43Na3O11
CAS
nd
MW
776.7 g/mol
Ka
na
Percent composition
C, 64.94; H, 5.58; N, 8.88; O, 20.61

Product specifications

Physical state
Beige powder
Purity (HPLC 214nm)
95%
Retention time (RP18 HPLC)
17.75 min
CMC
2.2 Mm
Exact mass
776.2549 g/mol
Stability
For Research Only
Solubility structure
Soluble in methanol, DMSO and water.
Datasheets
40-D101P
Datasheet
€ 1 320,00 EUR
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