SOLUBILIZATION AND STABILIZATION SCREENING KIT
CALIXAR’s screening kit helps to find the most suitable combination of CALIXAR’s reagents to extract and stabilize membrane proteins.
Reach high solubility rate, increase your protein stability for your scientific projects with accurate results to discover new drugs (small molecules, antibodies, …) and to open new therapeutic pathways.
Compound name: CALIXAR™ Screening Kit
Catalogue number: CALIXAR-K1
Including reagents: 5 soft proprietary detergents and 5 soft proprietary stabilization reagents
Chemical structures: CALX8, DDTAC, DDG, DLAC, FLAC6, FTAC6, FTAC8, DDLAC, CALXCHOL, CALXGLUK
MW: 497.6 – 2582 (g/mol)
Volume: CALXK1 is presented as a 10 x 100 µL microfuge tubes
For a typical 10-wells experiment: Add 250 µg of membrane protein sample, 10 µL of soft proprietary detergent and complete with buffer of choice to 50 µL.
For stabilization experiment also add 10µL of soft proprietary and stabilization reagent.
Stability: Long term storage at -20 ° C.
Solubility: Provided in solution.
Working pH: Maintain pH between 6-9 for optimal results.
User guide and certificate of analysis will be including in your package.
€ 990.00 for 10 tests
Ships in 7 business days
You can purchase each reagent individually from our online catalog.
Why choose us?
CALIXAR’s solubilization and stabilization screening kit helps to extract and stabilize membrane therapeutic targets (GPCRs, ion channels, transporters, enzymes, …). This kit includes 5 soft proprietary detergents and 5 soft proprietary stabilization reagents to improve trials and research involving membrane proteins.
10 unique proprietary reagents produced by CHEM2STAB, a joint research lab between CALIXAR and Avignon University.
With 10 tests, our screening assay kit can be used to determine the best reagent or the most suitable combination of reagents to extract, solubilize and stabilize native and functional membrane proteins in a solution.
Thanks to these reagents, our clients can obtain pure and functional membrane proteins with high medical relevance to discover new drugs (small molecules, antibodies, vaccines, …).
CALIXAR’s screening assay kit is produced with 10 unique soft proprietary detergents and soft proprietary stabilization reagents. These molecules are specifically designed to extract and stabilize membrane proteins while preserving their functionalities.
CALIXAR™ Solubilization and Stabilization Screening Kit is used for research, drug discovery, and structural studies that are used in the life science fields. Particularly adapted for biotechnology companies, as well as for academic teams (structural biologists, pharmacologists, biochemists, virologists).
Lebaupain F. et al. 2006
Damian, M. et al. 2007
Abla M et al. 2008
Journal of Bioenergetics and Biomembranes
Talbot J.-C., et al. 2009
Institut de Biologie Structurale
Breyton C et al. 2013
Dauvergne J. 2014
Journal of Colloid and Interface Science
Abla M et al. 2015
Dauvergne J. 2015
Desuzinges Mandon E. et al. 2017
Pierre Guillet et al. 2019
Julien Dauvergne et al. 2019