SOLUBILIZATION AND STABILIZATION SCREENING KIT
CALIXAR’s screening kit helps to find the most suitable combination of CALIXAR’s reagents to extract and stabilize membrane proteins.
Reach high solubility rate, increase your protein stability for your scientific projects with accurate results to discover new drugs (small molecules, antibodies, …) and to open new therapeutic pathways.
Compound name: CALIXAR™ Screening Kit
Catalogue number: CALIXAR-K1
Including reagents: 6 proprietary mild detergents and 4 proprietary stabilization reagents
Chemical structures: CALX8, DDTAC, DDG, DLAC, FLAC6, ODG, FTAC6, FTAC8, DDLAC, CALXGLUK
MW: 497.6 – 2582 (g/mol)
Volume: CALIXAR-K1 is presented as a 10 x 100 µL microfuge tubes
For a typical 10-wells experiment: Add 250 µg of membrane protein sample, 10 µL of soft proprietary detergent and complete with buffer of choice to 50 µL.
For stabilization experiment also add 10µL of soft proprietary and stabilization reagent.
Stability: Long term storage at -20 ° C.
Solubility: Provided in solution.
Working pH: Maintain pH between 6-9 for optimal results.
User guide and certificate of analysis will be including in your package.
€ 370.00
Ships in 7 business days
You can purchase each reagent individually from our online catalog.
First in market
CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.
Better discovery
Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.
Why choose us?
CALIXAR’s solubilization and stabilization screening kit helps to extract and stabilize membrane therapeutic targets (GPCRs, ion channels, transporters, enzymes, …). This kit includes 6 proprietary mild detergents and 4 proprietary stabilization reagents to improve trials and research involving membrane proteins.
With 10 tests, our screening assay kit can be used to determine the best reagent or the most suitable combination of reagents to extract, solubilize and stabilize native and functional membrane proteins in a solution.
Thanks to these reagents, our clients can obtain pure and functional membrane proteins with high medical relevance to discover new drugs (small molecules, antibodies, vaccines, …).
CALIXAR’s screening assay kit contains 10 proprietary mild detergents and stabilization reagents. These molecules are specifically designed to extract and stabilize membrane proteins while preserving their functionalities.
CALIXAR™ Solubilization and Stabilization Screening Kit is used for research, drug discovery, and structural studies that are used in the life science fields. Particularly adapted for biotechnology companies, as well as for academic teams (structural biologists, pharmacologists, biochemists, virologists).
ACS Publications
Abla M et al. 2008
Journal of Bioenergetics and Biomembranes
Talbot J.-C., et al. 2009
Institut de Biologie Structurale
Breyton C et al. 2013
Proprietary patent
Dauvergne J. 2014
Journal of Colloid and Interface Science
Abla M et al. 2015
Proprietary patent
Dauvergne J. 2015
ANALYTICAL BIOCHEMISTRY
Desuzinges Mandon E. et al. 2017
LANGMUIR
Pierre Guillet et al. 2019
CHEMISTRY SELECT
Julien Dauvergne et al. 2019
Contact us
Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.
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