Membrane Protein
Biochemical Assays and Characterization Services

CALIXAR provides high-quality membrane protein biochemical assays and characterization services for scientists, researchers and who require physical characterization of their membrane protein targets of concern. Our services are primarily used for (bio)drug discovery and are conformed for use in pharmaceutical, biotechnology firms, as well as for life sciences academic teams.

CALIXAR's Membrane Protein Biochemical Assay and Protein Characterization Services

CALIXAR’s Biochemical Assay and Protein Characterization Services support pharmaceutical businesses, biotechnology firms, as well as academic teams to work with leading-quality and reliable targets at the discovery or clinical stages of (bio)tech discovery.

CALIXAR’s clients’ projects can be fully performed in any kind of biochemical assays or protein characterization that is needed. CALIXAR gathers all in one place, the know-how, and technology required to the drug discovery challenges, allowing to optimize timelines improve the success rate. CALIXAR will be your unique contact and that can deals with all your projects based on membrane proteins (no longer need for service providers localized at different sites).

If you find yourself in one of the following discovery or clinical stages, CALIXAR’s services are ideal for you:

  • Drug discovery (target validation, target production),
  • Antibody discovery (antigen validation, antigen production),
  • Clinical stage (binding studies).

These services are used by CALIXAR in the following stages (for Membrane Proteins):

  • Identification
  • Expression
  • Extraction
  • Solubilization
  • Purification
  • Stabilization
  • Crystallization
  • Cryo-EM

Employ CALIXAR’s membrane protein Biochemical Assays and Characterization Services to generate information regarding:

  • Identification of targets/antigens partners by Co-purification and mass spectrometry 
  • Characterization of (Western Blot, Coomassie Gel, SDS Page)
  • Purity levels evaluation
  • Aggregation/oligomerization state assessment by Native Page, SEC and SEC-MALS
  • Stability measurements (thermostability assays)
  • Homogenization degrees (DLS, Native Page, Electron Microscopy Characterization)
  • Functional activity (transport assays, radio binding assays, enzymatic assays, current/voltage clamp assays for ion channel).

Strict Assay Development and Membrane Protein Quality Controls

Obtain access to the first Native, wild-type, unmutated, untruncated and crystal-grade targets to enable structure investigation of membrane proteins alone and in complex with small molecule compounds or antibody fragments.

CALIXAR’s procedure provides pharmaceutical firms with the opportunity to work with high-quality and trustworthy assays for characterizing membrane targets or antigens, compatible with all requirements.

CALIXAR has mastered the use of best-in-class technology for membrane protein characterization. Our approach ensures compatibility with many different uses. We are also able to modify each assay to fit with the demands of our clients’ projects (quality, compatibility).

We have influential expertise in characterizing all types of membrane protein targets and can assist you to develop and implement new assays that are transferred to our clients.

Get access to CALIXAR Technology

All of our clients receive access to our proprietary technology and know-how. (7 patent families, more than 20 publications).

The CALIXAR® platform uses patented technology only possible for clients under explicit agreements (license, co-development, and services).

You can leverage CALIXAR’s proprietary technology as well as other leading-in-class membrane protein technology that is not found anyplace else on the market.

Gain access to our specific expertise with a strong track record and several types of membrane proteins. We are continuously integrating best-of-the-art membrane protein characterization technology for our clients’ projects. Our clients have access to all assays needed for their projects, all on one platform.

  • Save time and money by using our unique assay services all in the same place.
  • Possibility to develop customized assays (transferable to our clients).
  • Possibility to validate customers’ hits/leads and the quality of the proteins produced.