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Custom protein services
Design Your Project

Design Your Project

Your target / construct

Calixar offers multiple cleavable tags (His, Flag, Strep, Avi…) and/or protein-fusion (GFP, RFP…), and will assist you to select optimal options for your project.

Your production process

Calixar’s purification process includes solubilization and stabilization screening in various proprietary and commercial detergents and/or SMALPs. 1- or 2-step affinity purification followed by a size-exclusion chromatography ensures >90% purity degree.

Calixar’s quality control process includes:
✓ Purity evaluation
‍✓ Protein quantification
‍✓ Homogeneity determination
✓ Cryo-stability assay

‍In addition, Calixar can develop specific protein characterizations such as:
• Thermal shift assay
‍• Functional assay (enzymatic activity, proteoliposome ion flux assay
• Ligand binding assay (radiobinding, fluorescence polarization, microscale thermophoresis

From µg- to mg-scale production, Calixar will fit all your needs of proteins for your R&D developments.
Based on your final application, Calixar is able to deliver your purified target in various formats such as micelles of detergent, SMALPs, amphipols, nanodiscs and proteoliposomes.

Your information

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Custom protein services
Protein Construct
Protein Expression
Protein Solubilization
Protein Stabilization
Protein Purification
Protein Characterization
Large-Scale Protein Production
Protein Identification
Design Your Project
Expression of fully native proteins
Identification of relevant targets
Target functional isolation and stabilization
Active custom proteins
Structure-based drug discovery
Immunoassays
Vaccine development
Functional antigen discovery
Conformational antibody development
Expression of fully native proteins
Identification of relevant targets
Target functional isolation and stabilization
Active custom proteins
Structure-based drug discovery
Functional antigen discovery

Secure and boost
your discovery programs

Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.

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