Receptors
Receptors are essential in drug discovery and cancer therapy development, offering targets to modulate cellular signaling pathways for therapeutic benefit. Their structural biology reveals insights into protein function and aids in drug design. Moreover, in fundamental research, studying these receptors deepens our understanding of cellular mechanisms and identifies potential targets for therapeutic intervention. Eurofins CALIXAR ensures the high purity, functionality & stability of receptor proteins, advancing your therapy development and membrane protein research.
Product highlights
High Purity & Stability: validated by meticulous quality controls (SDS-PAGE, UV Spectrum…), ligand binding assays (Thermal Shift Assay, Cryo-Stability Assay…) & functional assays.
Wild-type & unmutated: accurately mimics its native counterpart, ensuring reliability in experimental results.
Diverse applications: from fundamental research (structure biology) to therapy development (antibody & drug discovery).
Comprehensive Support: our experts provide dedicated assistance in every aspect of your ion channel research journey.
Receptor's functions
Membrane protein receptors play a pivotal role in cellular communication, recognizing specific ligands (antigens, transmitting signals, and coordinating a wide array of physiological processes, including immune regulation, immune cell activation, and signal transduction, making them crucial targets for drug development and therapeutic intervention.
Membrane receptors serve as crucial targets for therapeutic approaches and drug development due to their central role in cellular signaling and regulation of physiological processes. By selectively targeting membrane receptors, therapeutic molecules can modulate key pathways involved in diseases such as cancer and autoimmune disorders, offering the potential for precise interventions with reduced off-target effects. Additionally, the diverse array of membrane receptors provides a rich landscape for developing targeted therapies, ranging from monoclonal antibodies to innovative modalities (bispecific antibodies and CAR-T cell therapy), thereby enabling tailored and potent treatment strategies for various medical conditions.
All actors involved in life science projects can benefit from purified membrane proteins: pharmaceutical companies, biotechnology companies, and academic research centers.
Receptor's applications
With their precise targeting of specific cells and signaling pathways, Eurofins CALIXAR’s Receptors are pivotal targets for therapeutic interventions in cancer and immune diseases, enabling the development and validation of new molecules and therapeutic antibodies.
Our receptors are mostly suited for various life science projects, including:
- Small molecule screening
- Antibody research
- Structural biology
With their full-length preservation, our receptors maintain integral functionality, ensuring optimal performance in drug development, antibody research, and vaccine discovery projects. Their high purity and stability reduces interferences, protein aggregation, and instability, thereby enhancing efficacy in discovery programs.
Secure and boost
your discovery programs
Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.
