Solubilizing Reagents

The Challenge of Membrane Proteins

Membrane proteins, including G protein-coupled receptors (GPCRs), ion channels, and transporters, are essential components of cellular membranes and play pivotal roles in biological processes. However, their hydrophobic nature makes them inherently challenging to work with, particularly when isolating and studying them in a soluble form.

Eurofins DiscoverX’s Solubilizing Reagent Product Portfolio

Eurofins DiscoverX offers an extensive and diverse range of solubilizing reagent products designed to meet the unique needs of researchers in the field of membrane protein research. Our solubilizing reagent-focused offerings include:

• Proprietary Solubilizing Reagents: Our proprietary solubilizing reagents are meticulously formulated to effectively solubilize membrane proteins while preserving their native conformation and biological activity. These reagents are engineered to address the specific challenges posed by different membrane protein classes.
• Custom Solubilization Services: We understand that each membrane protein presents unique challenges. Eurofins DiscoverX offers custom solubilization services, tailoring solubilization protocols to the specific requirements of your research project.
• Structural Studies: Investigate the three-dimensional structures of membrane proteins and their complexes with confidence, thanks to our solubilizing reagents designed for structural biology applications.

Applications

Our solubilizing reagent products find applications across a broad spectrum of research areas, including:

• Structural Biology: Facilitate the solubilization of membrane proteins for structural studies, such as X-ray crystallography, cryo-electron microscopy (cryo-EM), and nuclear magnetic resonance (NMR).
• Drug Discovery: Enable the study of membrane protein interactions with potential drug candidates to advance drug discovery efforts for various diseases.
• Functional Studies: Support functional assays and screenings by maintaining the native structure and functionality of membrane proteins during experiments.

The Eurofins DiscoverX Advantage

Eurofins DiscoverX’s solubilizing reagent products are distinguished by:

• Effectiveness: Our reagents are designed to achieve exceptional solubilization efficiency while preserving the native state of membrane proteins.
• Customization: Tailor-made solutions that address the distinct requirements of different membrane proteins and research projects.
• Technical Support: Our team of experts is committed to assisting you in every aspect of your membrane protein research journey, from solubilization to data analysis.