YopH, active
N-terminal GST-tagged recombinant, Yersinia full length YopH.
No items found.
Biological information
Background
YopH is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
GenBank Y00551. The recombinant protein contains the amino acid substitution R211A with reference to Y00551. This mutation is reported inGenBank M30457.
Target class
Phosphatase
Family
Tyr phosphatase
Accession number
NP_783699
Target Name
YopH, active
Target Alias
Origin
Theori. MW
77.4 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed in E. coli
Purity
Purity 94% by
SDS-PAGE and Coomassie blue staining.
MW = 77.4kDa
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
YopH is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
GenBank Y00551. The recombinant protein contains the amino acid substitution R211A with reference to Y00551. This mutation is reported inGenBank M30457.
Compound name
Phosphatase
Catalog number
14-590
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-590
Datasheet