PTPMEG-2
N-terminal GST-tagged recombinant, human PTP-MEG2, amino acid amino acids 283-end.
No items found.
Biological information
Background
PTPMEG-2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
GenBank NM_002833
Target class
Phosphatase
Family
Tyr phosphatase
Accession number
NM_002833.2
Target Name
PTPMEG-2
Target Alias
PTPN9, PTPase-MEG2, MEG2
Origin
Human
Theori. MW
62.5 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed in E. coli
Purity
Refer to CoA for Purity
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
PTPMEG-2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
GenBank NM_002833
Compound name
Phosphatase
Catalog number
14-592
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-592
Datasheet