Fer, active
N-terminal 6His-tagged recombinant, human Fer amino acids 541-end.
No items found.
Biological information
Background
FER (TYK3) is a nuclear and cytoplasmic nonreceptor tyrosine kinase and able to affect transcription in the nucleus. FER is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, implicated in the regulation of myeloid differentiation. Inhibition of FER may be of benefit for the treatment of myeloid and prostate cancer as well as angiogenesis.
GenBank NM_005246
Target class
Kinase
Family
TK
Accession number
NM_005246.2
Target Name
Fer, active
Target Alias
FER, p94-FER, TYK3
Origin
Human
Theori. MW
35.6 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
FER (TYK3) is a nuclear and cytoplasmic nonreceptor tyrosine kinase and able to affect transcription in the nucleus. FER is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, implicated in the regulation of myeloid differentiation. Inhibition of FER may be of benefit for the treatment of myeloid and prostate cancer as well as angiogenesis.
GenBank NM_005246
Compound name
Kinase
Catalog number
14-605
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-605
Datasheet