ALK4, active
N-terminal GST-tagged recombinant, human ALK4 amino acids 150-end.
No items found.
Biological information
Background
On ligand binding, ALK4 forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
GenBank NM_004302
Target class
Kinase
Family
TKL
Accession number
NM_004302.3; NM_020327.2; NM_020328.2
Target Name
ALK4, active
Target Alias
ACVR1B, ALK-4, ACVRLK4, ALK4, SKR2, ActRIB, ACTR-IB, ACTRIB
Origin
Human
Theori. MW
63.8 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
On ligand binding, ALK4 forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
GenBank NM_004302
Compound name
Kinase
Catalog number
14-614
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-614
Datasheet