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Itk, active

N-terminal 6His-tagged recombinant, human Itk amino acids 352-617.

Biological information

Background
ITK (Interleukin-2-inducible T-cell kinase) is an important member of the Tec family of non-receptor tyrosine kinases that play a central role in signaling through antigen receptors such as the T-cell receptor, B-cell receptor, and Fce. GenBank NM_005546
Target class
Kinase
Family
TK
Accession number
NM_005546.3
Target Name
Itk, active
Target Alias
ITK, LYK, PSCTK2, EMT, MGC126258, MGC126257
Origin
Human
Theori. MW
34 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
ITK (Interleukin-2-inducible T-cell kinase) is an important member of the Tec family of non-receptor tyrosine kinases that play a central role in signaling through antigen receptors such as the T-cell receptor, B-cell receptor, and Fce. GenBank NM_005546
Compound name
Kinase
Catalog number
14-660
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-660
Datasheet
€ 389,00 EUR
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