EphB1, active
N-terminal 6His-tagged recombinant, human EphB1 amino acids 564-end.
No items found.
Biological information
Background
Eph (erythropoietin-producing hepatocellular) family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Among them, only EphA4 can cross-respond to both ephrin-A and -B. EphB1 (EPHT2, NET, Hek6, ELK) is expressed predominantly in developing neural structures in embryos, in vascular epithelium of kidney and other tissues. EphB1 signals regulation of cell attachment and cell-cell assembly and are implicated in neuronal and vascular cell targeting.
GenBank NM_004441
Target class
Kinase
Family
TK
Accession number
NM_004441.3
Target Name
EphB1, active
Target Alias
EPHB1, Hek6, EPHT2, NET, Elk, FLJ37986, ELK, EphB1, HEK6
Origin
Human
Theori. MW
51.4 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Eph (erythropoietin-producing hepatocellular) family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Among them, only EphA4 can cross-respond to both ephrin-A and -B. EphB1 (EPHT2, NET, Hek6, ELK) is expressed predominantly in developing neural structures in embryos, in vascular epithelium of kidney and other tissues. EphB1 signals regulation of cell attachment and cell-cell assembly and are implicated in neuronal and vascular cell targeting.
GenBank NM_004441
Compound name
Kinase
Catalog number
14-674
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-674
Datasheet