HIPK1, active
N-terminal 6His-tagged recombinant, human HIPK1 amino acids 158-555.
No items found.
Biological information
Background
HIPK1 (Homeodomain Interacting Protein Kinase 1) belongs to the Ser/Thr family of protein kinases and HIPK subfamily. HIPK1 is involved in transcription regulation and TNF-mediated cellular apoptosis and plays a role as a corepressor for homeodomain transcription factors. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors.
GenBank NM_152696
Target class
Kinase
Family
CMGC
Accession number
NM_152696.3; NM_181358.1; NM_198268.1; NM_198269.1
Target Name
HIPK1, active
Target Alias
HIPK1, MGC33446, KIAA0630, Nbak2, MGC26642, MGC33548, Myak
Origin
Human
Theori. MW
49.6 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
HIPK1 (Homeodomain Interacting Protein Kinase 1) belongs to the Ser/Thr family of protein kinases and HIPK subfamily. HIPK1 is involved in transcription regulation and TNF-mediated cellular apoptosis and plays a role as a corepressor for homeodomain transcription factors. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors.
GenBank NM_152696
Compound name
Kinase
Catalog number
14-679
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-679
Datasheet