Cdk9/Cyclin T1, active
C-terminal 6His-tagged recombinant, human full length cdk9 co-expressed with untagged, full length human cyclin T1.
No items found.
Biological information
Background
Members of the cyclin-dependent kinase pair CDK9/cyclinT1, also called positive transcription elongation factor b (P-TEFb), facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP.
GenBank AF517840 / GenBank NM_001240
Target class
Kinase
Family
CMGC
Accession number
NM_001261.2
Target Name
Cdk9/Cyclin T1, active
Target Alias
CDK9, C-2k, PITALRE, TAK, CDC2L4, C-2K
Origin
Human
Theori. MW
44 kDa (cdk9), 80.79 kDa (cyclinT1)
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Members of the cyclin-dependent kinase pair CDK9/cyclinT1, also called positive transcription elongation factor b (P-TEFb), facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP.
GenBank AF517840 / GenBank NM_001240
Compound name
Kinase
Catalog number
14-685
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-685
Datasheet