DAPK1, active
N-terminal GST-tagged recombinant, human DAPK1 amino acids 1-296.
No items found.
Biological information
Background
Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin-dependent kinase that phosphorylates serine/threonine residues on proteins. DAPK1 modulates cell death induced by IFN-γ, TNF-α, Fas, and detachment from the extracellular matrix. DAPK1 has been also implicated in TGF-β-induced apoptosis in several cultured cell lines in which Smad proteins mediate transcriptional activation of DAPK1.
GenBank NM_004938
Target class
Kinase
Family
CAMK
Accession number
NM_004938.2
Target Name
DAPK1, active
Target Alias
DAPK1, DAPK, DKFZp781I035
Origin
Human
Theori. MW
60.9 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin-dependent kinase that phosphorylates serine/threonine residues on proteins. DAPK1 modulates cell death induced by IFN-γ, TNF-α, Fas, and detachment from the extracellular matrix. DAPK1 has been also implicated in TGF-β-induced apoptosis in several cultured cell lines in which Smad proteins mediate transcriptional activation of DAPK1.
GenBank NM_004938
Compound name
Kinase
Catalog number
14-692
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-692
Datasheet