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CaM Kinase IIβ, active

N-terminal 6His-tagged recombinant CaM Kinase IIβ amino acids 1-315.

Biological information

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Target class
Kinase
Family
CAMK
Accession number
AF081572
Target Name
CaM Kinase IIβ, active
Target Alias
CAMK2B, CAMKB, CAM2, MGC29528, CAMK2
Origin
Human
Theori. MW
39.6 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Compound name
Kinase
Catalog number
14-718
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-718
Datasheet
€ 389,00 EUR
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