CLK3, active
N-terminal 6His-tagged recombinant, human full length CLK3.
Biological information
Background
CLK3 (CDC Like Kinase 3) is a dual specificity protein kinase which is involved in gene splicing regulation. The CLK family has four family members: CLK1/STY, CLK2, CLK3 and CLK4. CLKs are useful targets for studying diseases attributed to gene mis-splicing events.
GenBank NM_003992. The CLK3 construct contains the translational conflicts T132S and G133S with respect to the accession number given. These are both reported in GB BC019881.
Target class
Kinase
Family
CMGC
Accession number
NM_001292.1; NM_003992.1
Target Name
CLK3, active
Target Alias
CLK3, FLJ22858, clk3
Origin
Human
Theori. MW
63 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
CLK3 (CDC Like Kinase 3) is a dual specificity protein kinase which is involved in gene splicing regulation. The CLK family has four family members: CLK1/STY, CLK2, CLK3 and CLK4. CLKs are useful targets for studying diseases attributed to gene mis-splicing events.
GenBank NM_003992. The CLK3 construct contains the translational conflicts T132S and G133S with respect to the accession number given. These are both reported in GB BC019881.
Compound name
Kinase
Catalog number
14-724
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-724
Datasheet