CaM Kinase Iδ, active
N-terminal 6His-tagged recombinant, human full length CaM Kinase Iδ.
No items found.
Biological information
Background
CaM Kinase Iδ Protein is a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. May be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
GenBank NM_153498
Target class
Kinase
Family
CAMK
Accession number
NM_020397.2; NM_153498.2
Target Name
CaM Kinase Iδ, active
Target Alias
CAMK1D, CaM-K1, CaMKI-delta, Camk1D, CKLiK, OTTHUMP00000045030, CaMKID
Origin
Human
Theori. MW
46.7 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Protein in 50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
CaM Kinase Iδ Protein is a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. May be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
GenBank NM_153498
Compound name
Kinase
Catalog number
14-731
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-731
Datasheet