AMPK (α2, β1, γ1), active
Recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 and full length untagged AMPKγ1.
No items found.
Biological information
Background
AMPK (α2, β1, γ1) is a metabolic master switch, activated by exercise and muscle contraction. AMPK phosphorylate key target proteins that control glucose uptake, oxidation of fatty acids, cholesterol synthesis, lipogenesis, triglyceride synthesis, adipocyte lipolysis, glycolysis and nitric oxide synthesis.
GenBank NM_006252 / GenBank NM_006253 / GenBank NM_002733
Target class
Kinase
Family
CAMK
Accession number
NM_006252; NM_006253; NM_002733
Target Name
AMPK (α2, β1, γ1), active
Target Alias
PRKAB1, PRKAG1 , PRKAA2
Origin
Human
Theori. MW
63 kDa (AMPKα2), 30 kDa (AMPKß1), 38 kDa (AMPKγ1)
Affinity tag
6His
Product specifications
Expression system
Expressed in E. coli cells and activated in vivo
Purity
Refer to CoA for Purity
Purification method
Cobalt-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
AMPK (α2, β1, γ1) is a metabolic master switch, activated by exercise and muscle contraction. AMPK phosphorylate key target proteins that control glucose uptake, oxidation of fatty acids, cholesterol synthesis, lipogenesis, triglyceride synthesis, adipocyte lipolysis, glycolysis and nitric oxide synthesis.
GenBank NM_006252 / GenBank NM_006253 / GenBank NM_002733
Compound name
Kinase
Catalog number
14-902
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-902
Datasheet