CDKL1, active
10 µg of active CDKL1. N-terminal 6His-tagged, recombinant, human CDKL1 amino acids 1-303.
Biological information
Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Target class
Kinase
Family
Ser/Thr Kinase
Accession number
NM_004196.3
Target Name
CDKL1, active
Target Alias
Cyclin Dependent Kinase Like 1KKIALRECyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)Protein Kinase P42 KKIALRESerine/Threonine Protein Kinase KKIALRE
Origin
Human
Theori. MW
39kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
83% by SDS-PAGE and Coomassie blue staining
Purification method
Purified using immobilized metal affinity chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Compound name
Kinase
Catalog number
16-002
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-002
Datasheet