ACTR2, active
10 µg of active ACTR2. N-terminal GST-tagged, recombinant, human ACTR2 amino acids 162-end.
Biological information
Background
Actin-related protein 2 (ACTR2) is a protein that in humans is encoded by the ACTR2 gene. The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Target class
Kinase
Family
TKL
Accession number
NM_001616.2
Target Name
ACTR2, active
Target Alias
Actin Related Protein 2; ARP2 Actin Related Protein 2 Homolog; ARP2; Actin-Related Protein 2
Origin
Human
Theori. MW
66 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
93% by SDS-PAGE and Coomassie blue staining
Purification method
glutathione agarose
Sample Buffer
enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
Actin-related protein 2 (ACTR2) is a protein that in humans is encoded by the ACTR2 gene. The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Compound name
Kinase
Catalog number
16-009
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-009
Datasheet