CDK16/cyclin Y, active
10 µg of active CDK16/cyclin Y. N-terminal GST-tagged, recombinant, human CDK16 full length and N-terminal GST-tagged, recombinant, human cyclin Y full length.
Biological information
Background
CDK16, cyclin dependent kinase 16, belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It plays a role in vesicle-mediated transport processes and exocytosis. It also plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. [provided by RefSeq, Dec 2009]
Target class
Kinase
Family
CMGC
Accession number
NM_033018.1
Target Name
CDK16/cyclin Y, active
Target Alias
Cyclin Dependent Kinase 16; PCTAIRE1; PCTGAIRE; PCTK1
Origin
Human
Theori. MW
83 kDa (CDK16), 67 kDa (cyclin Y)
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
89% by SDS-PAGE and Coomassie blue staining
Purification method
glutathione agarose
Sample Buffer
2.19mg/ml of enzyme in 50mM Tris/HCl pH8.0, 4mM glutathione, 266mM NaCl, 0.09mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.9mM benzamidine, 0.2mM PMSF, 0.09% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
CDK16, cyclin dependent kinase 16, belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It plays a role in vesicle-mediated transport processes and exocytosis. It also plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. [provided by RefSeq, Dec 2009]
Compound name
Kinase
Catalog number
16-041
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-041
Datasheet