CDK17/cyclin Y, active
10 µg of active CDK17/cyclin Y. N-terminal GST-tagged, recombinant, human CDK17 full length and N-terminal GST-tagged, recombinant, human cyclin Y full length.
Biological information
Background
CDK17, cyclin dependent kinase 17, belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in terminally differentiated neurons and has a Ser/Thr-phosphorylating activity for histone H1 (By similarity). [provided by RefSeq, Jul 2010]
Target class
Kinase
Family
CMGC
Accession number
BC033005.1
Target Name
CDK17/cyclin Y, active
Target Alias
Cyclin Dependent Kinase 17; PCTAIRE2; PCTK2; Serine/Threonine-Protein Kinase PCTAIRE-2
Origin
Human
Theori. MW
87 kDa (CDK17), 67 kDa (cyclin Y)
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
80% by SDS-PAGE and Coomassie blue staining
Purification method
glutathione agarose
Sample Buffer
1.11mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
CDK17, cyclin dependent kinase 17, belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in terminally differentiated neurons and has a Ser/Thr-phosphorylating activity for histone H1 (By similarity). [provided by RefSeq, Jul 2010]
Compound name
Kinase
Catalog number
16-042
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-042
Datasheet