CK1ε, active
10 µg of active CK1ε. N-terminal GST-tagged, recombinant, human CK1e amino acids 1-348.
Biological information
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession number
NM_001894.4
Target Name
CK1ε, active
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theori. MW
67kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Compound name
Kinase
Catalog number
16-045
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-045
Datasheet