Xtract-CALX8

CALX8 or 5,11,17-tris[(carboxy)methyl]-25-monooctyloxy-26,27,28-trihydroxycalix[4]arene solubilizing reagent is a calixarene based detergent/surfactant with three polar carboxylic groups and a octyl chain. This detergent is adapted to extract, to solubilize or to stabilize precise membrane proteins. The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time. CALX8 is in powder form and is used in an aqueous solution or buffer. It can be combined with biological materials (such as biological membranes). CALX8 is very mild detergent to secure, to solubilize and to preserve native membrane proteins which is ideal for extraction, to solubilization and to stabilization of particular membrane proteins. Our clients are able to use CALX8 to assist in the development of lipids-detergents mixed micelles, and protein detergent micelles.