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Xtract-DDG

Xtract-DDG solubilizing reagent

Biological information

Background

Xtract-DDG or N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(decylthio)propanamide solubilizing reagent is a non-ionic amphiphilic detergent and surfactant with a di-glucose polar group and decyl chain.  Hence is not sensitive to ionic strengths or pH variations. It is well conformed to extract, to solubilize and to stabilize specific membrane proteins  of exceptional medical relevance. DDG is in a powder application and is used in an aqueous solution or buffer. DDG can be coupled with biological elements (biological membranes). Our clients use DDG to help create lipids-detergents mixed micelles, and protein detergent micelles. DDG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science fields.

Target class
Solubilizing Reagent
Family
Accession number
Target Name
Xtract-DDG
Target Alias
Origin
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
For Research Only
Storage conditions
Store in <-20°C freezer out of direct light
Usage disclaimer
For Research Only

Chemical data

Background

Xtract-DDG or N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(decylthio)propanamide solubilizing reagent is a non-ionic amphiphilic detergent and surfactant with a di-glucose polar group and decyl chain.  Hence is not sensitive to ionic strengths or pH variations. It is well conformed to extract, to solubilize and to stabilize specific membrane proteins  of exceptional medical relevance. DDG is in a powder application and is used in an aqueous solution or buffer. DDG can be coupled with biological elements (biological membranes). Our clients use DDG to help create lipids-detergents mixed micelles, and protein detergent micelles. DDG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science fields.

Compound name
Solubilizing Reagent
Catalog number
40-D201P-100MG
Molecular formula
C29H55NO13S
CAS
nd
MW
657.8 g/mol
Ka
na
Percent composition
C, 52.95; H, 8.43; N, 2.13; O, 31.62; S, 4.87

Product specifications

Physical state
White powder
Purity (HPLC 214nm)
97.5%
Retention time (RP18 HPLC)
14.6 min
CMC
0.54 mM
Exact mass
657.3394 g/mol
Stability
For Research Only
Solubility structure
Soluble in water (27mM), methanol and DMSO.
Datasheets
40-D201P
Datasheet
€ 69,00 EUR
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