Xtract-DDTAC
Xtract-DDTAC solubilizing reagent
Biological information
Background
DDTAC or Dodecylmercapto-S-(poly(tris(hydroxymethyl)acrylamidomethane) DPn=6 solubilizing reagent is a non-ionic detergent that can be used to solubilize, extract and stabilize membrane proteins (GPCRs, Ion channels, Transporters, ….). DDTAC is in a powder application and is used in an aqueous solution or buffer. DDTAC can be coupled with biological elements (biological membranes). Our clients use DDTAC to help create lipids-detergents mixed micelles, and protein detergent micelles. DDTAC extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science fields.
Target class
Solubilizing Reagent
Family
Accession number
Target Name
Xtract-DDTAC
Target Alias
Origin
Theori. MW
Affinity tag
Product specifications
Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
For Research Only
Storage conditions
Store in <-20°C freezer out of direct light
Usage disclaimer
For Research Only
Chemical data
Background
DDTAC or Dodecylmercapto-S-(poly(tris(hydroxymethyl)acrylamidomethane) DPn=6 solubilizing reagent is a non-ionic detergent that can be used to solubilize, extract and stabilize membrane proteins (GPCRs, Ion channels, Transporters, ….). DDTAC is in a powder application and is used in an aqueous solution or buffer. DDTAC can be coupled with biological elements (biological membranes). Our clients use DDTAC to help create lipids-detergents mixed micelles, and protein detergent micelles. DDTAC extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science fields.
Compound name
Solubilizing Reagent
Catalog number
40-D202P-250MG
Molecular formula
na
CAS
112-55-0
MW
1254 g/mol
Ka
na
Percent composition
na
Product specifications
Physical state
White powder
Purity (HPLC 214nm)
88%
Retention time (RP18 HPLC)
11.8 min
CMC
0.14 mM
Exact mass
na
Stability
For Research Only
Solubility structure
Soluble in water (15mM), methanol and DMSO.
Datasheets
40-D202P
Datasheet