Xtab-FTAC8
Xtab-FTAC8 stabilizing reagent
Biological information
Background
FTAC8 or S-(poly(tris(hydroxymethyl)acrylamidomethane)-
(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorothiodecyl) DPn=12 stabilizing reagent is a non-ionic detergent that is principally used to extract, solubilize and stabilize GPCRs, Ion channels, and Transporters. Therefore, this reagent is not susceptible to ionic strength variations or pH fluctuations. It is also able to stabilize specific membrane proteins due to the fluorinated chain. FTAC8 does not solubilize the lipid membrane. FTAC8 is a mild reagent well suited to stabilize many different specific membrane proteins. It is provided in powder form and is generally used in an aqueous solution or buffer. It can also be mixed within biological materials (biological membranes). It is also used as a protein chaperone to inject membrane proteins into liposomes. FTAC8 is a leading-quality detergent / reagent principally used in research and drug discovery projects.
Target class
Stabilizing Reagents
Family
Accession number
Target Name
Xtab-FTAC8
Target Alias
Origin
Theori. MW
Affinity tag
Product specifications
Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
For Research Only
Storage conditions
Store in <-20°C freezer out of direct light
Usage disclaimer
For Research Only
Chemical data
Background
FTAC8 or S-(poly(tris(hydroxymethyl)acrylamidomethane)-
(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorothiodecyl) DPn=12 stabilizing reagent is a non-ionic detergent that is principally used to extract, solubilize and stabilize GPCRs, Ion channels, and Transporters. Therefore, this reagent is not susceptible to ionic strength variations or pH fluctuations. It is also able to stabilize specific membrane proteins due to the fluorinated chain. FTAC8 does not solubilize the lipid membrane. FTAC8 is a mild reagent well suited to stabilize many different specific membrane proteins. It is provided in powder form and is generally used in an aqueous solution or buffer. It can also be mixed within biological materials (biological membranes). It is also used as a protein chaperone to inject membrane proteins into liposomes. FTAC8 is a leading-quality detergent / reagent principally used in research and drug discovery projects.
Compound name
Stabilizing Reagents
Catalog number
40-S203P-250MG
Molecular formula
na
CAS
nd
MW
≈2600 g/mol
Ka
na
Percent composition
na
Product specifications
Physical state
White powder
Purity (HPLC 214nm)
88%
Retention time (RP18 HPLC)
11.828 min
CMC
0.02 mM
Exact mass
na
Stability
For Research Only
Solubility structure
Soluble in water (1mM), methanol and DMSO
Datasheets
40-S203P
Datasheet