AcrB, ACTIVE
Recombinant Multidrug efflux pump subunit AcrB, full-length, wildtype sequence, C-terminus 6xHis-tag
No items found.
Biological information
Background
Acridine resistance protein B (Multidrug efflux pump subunit AcrB) is a bacterial multidrug exporter that aids in the identification, development, refinement, and validation of new molecules and therapeutic antibodies. Our AcrB transporters are exemplary for therapeutic indications such as bacterial resistance to antibiotics. Acridine resistance protein B is a bacterial multidrug exporter. The protein has a C-terminal 6X His tag. Acridine resistance protein B is unaltered, unmutated and untruncated targets that sustain their structural and functional integrity. This membrane protein transporter is purified and stabilized full length and wild-type (native), produced in a prokaryotic arrangement (E.coli). AcrB belongs to a protein complex which serves as a drug efflux system with a wide range of substrate compatibility. It harnesses the proton motive force to expel various substrates.
Target class
Transporter
Family
Multidrug efflux pump
Accession number
P31224
Target Name
AcrB, ACTIVE
Target Alias
AcrAB-TolC multidrug efflux pump subunit AcrB
Acridine resistance protein B
Origin
Escherichia coli (strain K12)
Theori. MW
114.6 kDa
Affinity tag
6xHis-tag
Product specifications
Expression system
Expressed in Escherichia coli ( BL21C43)
Purity
Purity >95% by SDS-PAGE, Stain-Free detection and Coomassie stain
Purification method
Immobilized Metal Affinity Chromatography
Sample Buffer
Protein in 25 mM Na2HPO4/NaH2PO4 pH 8.0, 150 mM NaCl, 0.01% DDM
Specified activity
Confirmed by ligand binding assay
Application
For Research Only
Storage conditions
Store at -80°C
Usage disclaimer
For Research Only
Chemical data
Background
Acridine resistance protein B (Multidrug efflux pump subunit AcrB) is a bacterial multidrug exporter that aids in the identification, development, refinement, and validation of new molecules and therapeutic antibodies. Our AcrB transporters are exemplary for therapeutic indications such as bacterial resistance to antibiotics. Acridine resistance protein B is a bacterial multidrug exporter. The protein has a C-terminal 6X His tag. Acridine resistance protein B is unaltered, unmutated and untruncated targets that sustain their structural and functional integrity. This membrane protein transporter is purified and stabilized full length and wild-type (native), produced in a prokaryotic arrangement (E.coli). AcrB belongs to a protein complex which serves as a drug efflux system with a wide range of substrate compatibility. It harnesses the proton motive force to expel various substrates.
Compound name
Transporter
Catalog number
41-T401A-10UG
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
41-T401A
Datasheet