Soft Proprietary Detergents

DLAC Reagent

CALIXAR’s DLAC reagent is a non-ionic detergent / surfactant with a lactobionamide head group and a decyl chain.

Purchase DLAC reagent

N-decylamine lactobionamide

Compound name: N-decylamine lactobionamide (DLAC)

Catalogue number: DLAC _250MG
DLAC_ 500MG
DLAC_1G

Molec. Formula: C22H43NO11

CAS: nd

MW: 497.6 g/mol

pKa: na​

Percent Composition: C, 53.1; H, 8.71; N, 2.81; O, 35.37

Physical state: White powder

Purity (HPLC, 214nm): 97%

Retention time (RP18 HPLC)b: R = 10.6 min

CMC: 1.3 mM

Exact mass: 497.2836

Stability: Store in <-20°C out of direct light

Solubility Structure: Soluble in water (65mM), methanol and DMSO

Datasheet

€ 180.00 (250mg)

ships in 7 business days

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First in market

CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.

Better discovery

Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.

Why choose us?

We use a unique & custom-established procedure to give us the edge

CALIXAR’s DLAC is provided to clients in a powder form and is used in aqueous solutions or buffers. DLAC can be processed with biological materials (biological membranes).

Our clients are able to use DLAC to better produce lipid detergents, mixed micelles, and protein detergent micelles. DLAC provides our clients with a way to extract, to solubilize and to stabilize native and functional membrane proteins.

DLAC is a quite mild detergent to extract, to solubilize and to stabilize native membrane proteins. As DDLAC is non-ionic. Therefore, it is not sensitive to ionic strength or pH variations which is ideal to extract, to solubilize and to stabilize specific membrane proteins of high medical relevance.

CALIXAR’s DLAC is non-ionic and therefore not susceptible to ionic strength or pH variations. It is specifically built to extract, solubilize and stabilize precise membrane proteins.

CALIXAR’s DLAC (N-decylamine lactobionamide) extracts high-quality membrane proteins utilized for research, drug discovery projects and structural studies. They are used by pharmaceutical firms, biotechnology companies, and academic teams (biochemists, structural biologists, pharmacologists, virologists) that are committed to the life science disciplines.

  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage

References

ACS Publications

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006

Read more

Contact us

Secure and boost your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.

  • Conformational antibody development
  • Vaccine development
  • High-throughput ligand screening
  • Structure-based drug discovery
  • Immunoassays
  • Deorphanization projects
  • Identification of relevant targets
  • Expression of full-length membrane proteins
  • Functional isolation and stabilization of targets

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Or leave us an email : contact(at)calixar.com