Soft Proprietary Detergents

DLAC Reagent

CALIXAR’s DLAC reagent is a non-ionic detergent / surfactant with a lactobionamide head group and a decyl chain.

Purchase DLAC reagent

N-decylamine lactobionamide

Compound name: N-decylamine lactobionamide (DLAC)

Catalogue number: DLAC _250MG
DLAC_ 500MG
DLAC_1G

Molec. Formula: C22H43NO11

CAS: nd

MW: 497.6 g/mol

pKa: na​

Percent Composition: C, 53.1; H, 8.71; N, 2.81; O, 35.37

Physical state: White powder

Purity (HPLC, 214nm): 97%

Retention time (RP18 HPLC)b: R = 10.6 min

CMC: 1.3 mM

Exact mass​: 497.2836

Stability: Store in <-20°C freezer for up to one year

Solubility Structure: Soluble in water (65mM), methanol and DMSO

€ 180.00 (250mg)

ships in 7 business days

First in market

CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.

Better discovery

Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.

Why choose us?

We use a unique & custom-established procedure to give us the edge

CALIXAR’s DLAC is provided to clients in a powder form and is used in aqueous solutions or buffers. DLAC can be processed with biological materials (biological membranes).

Our clients are able to use DLAC to better produce lipid detergents, mixed micelles, and protein detergent micelles. DLAC provides our clients with a way to extract, to solubilize and to stabilize native and functional membrane proteins.

DLAC is a quite mild detergent to extract, to solubilize and to stabilize native membrane proteins. As DDLAC is non-ionic. Therefore, it is not sensitive to ionic strength or pH variations which is ideal to extract, to solubilize and to stabilize specific membrane proteins of high medical relevance.

CALIXAR’s DLAC is non-ionic and therefore not susceptible to ionic strength or pH variations. It is specifically built to extract, solubilize and stabilize precise membrane proteins.

CALIXAR’s DLAC (N-decylamine lactobionamide) extracts high-quality membrane proteins utilized for research, drug discovery projects and structural studies. They are used by pharmaceutical firms, biotechnology companies, and academic teams (biochemists, structural biologists, pharmacologists, virologists) that are committed to the life science disciplines.

  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage

References

ACS Publications

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006

Membrane Protein Purchase

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Give us a call : +33 481 076 460

Or leave us an email : contact(at)calixar.com