Soft Proprietary Detergents

ODG Reagent

CALIXAR’s ODG reagent is a non-ionic amphiphilic detergent / surfactant with a diglucose polar group and an octyl chain.

Purchase ODG reagent

N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(octylthio)propanamide

Compound name: ODG

Catalogue number: ODG_100MG
ODG_250MG
ODG_500MG
ODG_1G

Molec. Formula: C27H51NO13S

CAS: nd

MW: 629.8 g/mol

pKa: na​

Percent Composition: C, 51.49; H, 8.16; N, 2.22; O, 33.03; S, 5.09

Physical state: White powder

Purity (HPLC, 214nm): ≥95%

Retention time (RP18 HPLC)b: tR = 12.9 min

CMC: >10 mM

Exact mass: 629.3081

Stability: Store in <-20°C freezer out of direct light

Solubility Structure: Soluble in water (0.5M), methanol and DMSO.

Datasheet

€ 180.00 (100mg)

€ 330.00 (250mg)

Ships in 7 business days

Purchase

First in market

CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.

Better discovery

Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.

Why choose us?

We use a novel & tailored approach to give you an edge

CALIXAR’s ODG is manufactured in a powder form and is used in aqueous solution or buffer. ODG can be processed with biological materials (biological membranes).

Our clients are able to use ODG to help produce lipid detergents, mixed micelles, and protein detergent micelles. ODG allows clients to extract, to solubilize and to stabilize native and functional membrane proteins in solution.

CALIXAR’s ODG is very mild detergent to extract, to solubilize and to stabilize native membrane proteins and is non-ionic. Accordingly, it is not sensitive to ionic concentration or pH fluctuations which is excellent to extract, to solubilize and to stabilize specific membrane proteins.

Our ODG can extract, solubilize and stabilize more efficiently delicate membrane proteins of high medical relevance.

CALIXAR’s ODG is non-ionic and therefore is not receptive to ionic strength or pH variations and could be well adapted to extract, to solubilize and to stabilize specific membrane proteins.

CLAIXAR’s ODG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.

  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage

References

ACS Publications

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006

Read more

Contact us

Secure and boost your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.

  • Conformational antibody development
  • Vaccine development
  • High-throughput ligand screening
  • Structure-based drug discovery
  • Immunoassays
  • Deorphanization projects
  • Identification of relevant targets
  • Expression of full-length membrane proteins
  • Functional isolation and stabilization of targets

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Membrane Protein Purchase

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Give us a call : +33 481 076 460

Or leave us an email : contact(at)calixar.com