Soft Proprietary Stabilization Reagents
CALIXAR’s CALXGLUK is a calixarene detergent that can be used to solubilize membrane protein as GPCR.
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Compound name: CALXGLUK
Catalogue number: CALXGLUK_10MG,
CALXGLUK_50MG,
CALXGLUK_100MG
Molec. Formula: C71H95N9O22
CAS: nd
MW: 1426.5 g/mol
pKa: na
Percent Composition: C, 59.78; H, 6.71; N, 8.84; O, 24.67
Physical state: Beige powder
Purity (HPLC, 214nm): <95%
Retention time (RP18 HPLC)b: tR = 13.4 min
CMC: 0.025 mM
Exact mass: 1425.6592
Stability: Store in <-20°C freezer for up to one year
Solubility Structure: Soluble in water (2.5mM), methanol and DMSO
€450.00 (10mg)
€ 1,200.00 (50mg)
€ 1,900.00 (100mg)
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First in market
CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.
Better discovery
Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.
Why choose us?
CALIXAR’s CALXGLUK is a very gentle detergent used to stabilize native membrane proteins. CALXGLUK is non-ionic and hence is not sensitive to ionic strength or pH fluctuations is well adapted to stabilize many different specific membrane proteins.
Calixar’s CALXGLUK can help deliver lipid detergent mixed micelles and protein detergent micelles. CALXGLUK also provides for the stabilization of native and functional membrane proteins within a solution.
Our CALXGLUK is provided in a powder form and is used in an aqueous solution or buffer which can also be mixed within biological substances (biological membranes).
CALXGLUK is a non-ionic calixarene based detergent / surfactant with three polar glucose groups and a heptyl chain.
CALIXAR’s CALXGLUK is non-ionic and therefore is not sensitive to ionic strength or pH variations and is able to stabilize specific membrane proteins. Due to the fluorinated chain, CALXGLUK does not solubilize lipid membranes.
CALIXAR’s CALXGLUK is a high-quality detergent / reagent utilized for research, drug discovery projects, and structural studies. Our technology is adapted for use in pharmaceutical and biotechnology companies, as well as for life science academic teams (biochemists, structural biologists, pharmacologists, virologists).
Proprietary patent
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Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.
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