Soft Proprietary Stabilization Reagents
CALIXAR’s FTAC6 Reagent is a non-ionic detergent that is primarily used to extract, solubilize and stabilize GPCRs, Ion channels, and Transporters.
Compound name: FTAC6
Catalogue number: FTAC6_250MG,
Molec. Formula: C6F13CH2CH2CH2
MW: ≈1400 g/mol
Percent Composition: na
Physical state: White powder
Purity (HPLC, 214nm): nd
Retention time (RP18 HPLC)b: tR = 10.5 min min
CMC: 0.37 mM
Exact mass: nd
Stability: Store in <-20°C freezer out of direct light
Solubility Structure: Soluble in water (18.5mM), methanol and DMSO
€ 150.00 (250mg)
ships in 7 business days
Why choose us?
CALIXAR’s FTAC6 is a very soft detergent used to stabilize native membrane proteins. FTAC6 is non-ionic and therefore not sensitive to ionic strength or pH variations is well adapted to stabilize many different specific membrane proteins. Due to the fluorinated chain, FTAC6 is poorly delipidating towards membrane proteins.
Our FTAC6 can improve the production of lipid detergents, mixed micelles, and protein detergent micelles. FTAC6 allows for the stabilization of native and functional membrane proteins in a solution.
Our FTAC6 is provided in powder form and will be used in an aqueous solution or buffer and can also be mixed within biological materials (biological membranes).
CALIXAR’s FTAC6 is non-ionic and consequently not sensitive to ionic strength or pH fluctuations and is able to stabilize specific membrane proteins. Due to the fluorinated chain, FTAC6 does not solubilize lipid membranes.
CALIXAR’s FTAC6 is a high-quality detergent / reagent used for research and pharmaceutical discovery projects. Our structural studies and are adapted for use in biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science fields.
Damian, M. et al. 2007
Biochimica Et Biophysica Acta-Biomembranes
Joubert O. et al. 2009
Park K.-H. et al. 2007