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Soft Proprietary Stabilization Reagents
FTAC8 is a non-ionic detergent that is principally used to extract, solubilize and stabilize GPCRs, Ion channels, and Transporters.
Compound name: FTAC8
Catalogue number: FTAC8_250MG,
FTAC8_500MG,
FTAC8_1G
Molec. Formula: C8F17CH2CH2
CAS: nd
MW: ≈2600 g/mol
pKa: na
Percent Composition: na
Physical state: White powder
Purity (HPLC, 214nm): nd
Retention time (RP18 HPLC)b: tR = 11.7 min min
CMC: 0.02 mM
Exact mass: nd
Stability: Store in <-20°C freezer for up to one year
Solubility Structure: Soluble in water (1mM), methanol and DMSO
€ 150.00 (250mg)
ships in 7 business days
First in market
CALIXAR is the first to produce native, wild-type, unmutated and untruncated targets.
Better discovery
Develop reliable and effective drugs and antibodies as they are not locked in any specific conformation.
Why choose us?
CALIXAR’s FTAC8 is a rather mild detergent utilized to stabilize native membrane proteins. FTAC8 is non-ionic and therefore not susceptible to ionic strength fluctuations or pH variations. They are also well suited to stabilize many different particular membrane proteins. Due to the fluorinated chain, FTAC8 is poorly delipidating towards membrane proteins.
Our FTAC8 helps generate lipid detergent mixed micelles and protein detergent micelles. FTAC8 also allows for the stabilization of native and functional membrane proteins. It is also used as a protein chaperone to inject membrane proteins into liposomes.
CALIXAR’s FTAC8 is provided in powder form and is generally used in an aqueous solution or buffer. It can also be mixed within biological materials (biological membranes).
CALIXAR’s FTAC8 is non-ionic detergent and therefore is not susceptible to ionic strength variations or pH fluctuations. It is also able to stabilize specific membrane proteins due to the fluorinated chain. FTAC8 does not solubilize the lipid membrane.
CALIXAR’s FTAC8 is a leading-quality detergent / reagent principally used in research and drug discovery projects. Our structural studies and are adapted for use in pharmaceutical and biotechnology companies, as well as for life science academic teams (biochemists, structural biologists, virologists, pharmacologists).
Febs Letters
Damian M. et al. 2007
Biochimica Et Biophysica Acta-Biomembranes
Joubert O. et al. 2009
Biochemical Journal
Park K.-H. et al. 2007
Contact us
Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ions Channels, Transporters, Receptors and Viral Proteins.
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