Purified Membrane Proteins

Dolichol phosphate-mannose biosynthesis regulatory protein

Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

DPM2_HUMAN

Gene Name:

DPM2

Uniprot Accession:

O94777

Origin:

Homo sapiens (Human)

Protein family:

DPM2

Full-length:

Mass:

9312

Sequence

MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGLFISYVMLKTKRVTKKAQ

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

Dolichol phosphate-mannose biosynthesis regulatory protein

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