Purified Membrane Proteins

Proton-coupled zinc antiporter SLC30A8

Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.

Native

Stable

Pure

Active protein

Recombinant protein

Human Origin

Entry Name:

ZNT8_HUMAN

Gene Name:

SLC30A8

Uniprot Accession:

Q8IWU4

Origin:

Homo sapiens (Human)

Protein family:

Cation diffusion facilitator (CDF) transporter (TC 2.A.4), SLC30A subfamily

Full-length:

369

Mass:

40755

Sequence

MEFLERTYLVNDKAAKMYAFTLESVELQQKPVNKDQCPRERPEELESGGMYHCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQRCLGHNHKEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD

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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

Proton-coupled zinc antiporter SLC30A8

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